Michael Yellen of AIM Global Health Care Fund

S&P Rank: 4 Stars Good Prognoses for Drug Stocks

Like the vast majority of asset classes, health care

stocks suffered a tough year in 2002, with the average mutual fund invested

in the sector dropping by 29.9%. The $734-million AIM Global Health Care

Fund/A (GGHCX), managed by Michael Yellen did relatively better, falling

22.7% on the year. Over the longer term, however, the picture is brighter.

For the three-year period ended 2002, the fund gained 7.2% on an average

annualized basis, versus a decline of 1.3% for its health care fund peers.

For the ten-year period, the fund returned 11.2% annualized, versus 10.8%

for its peers.

Once considered a defensive investment, health care stocks now appear

to be more affected by macroeconomic factors. However, the sector is broadly

diversified, including everything from big drug manufacturers to small firms

that make gauzes and stents. As a result, sub-sectors within health care

have different characteristics, and behave differently as well.

Yellen, a strictly bottom-up, value-oriented stock picker, is keeping

much of his money in the familiar, big-cap, blue-chip drug makers. Many of

these companies are at near-historic lows in terms of valuations, and as

people in the developed world continue to age in record numbers, they will

need more medicines and medical care. As a result, Yellen sees strong

outperformance from these stocks. His portfolio, which was launched in 1989,

carries an overall ranking of 4 Stars by Standard & Poor's.

The Full Interview:

S&P: What hurt health care and pharmaceutical stocks in 2002?

YELLEN: It was somewhat surprising that the health care sector

performed as poorly as it did in 2002, given that this has traditionally

been viewed as a defensive investment. The bulk of most health care funds

are invested in the large-cap, blue-chip, U.S. drug names, and these stocks

under-performed significantly last year.

Familiar companies like Merck (MRK), Schering-Plough (SGP), Bristol-Myers

(BMY), Eli Lilly (LLY) and Pfizer (PFE) all endured poor years. However,

their problems were due primarily to company-specific issues.

S&P: Can you give me an example?

YELLEN: Bristol-Myers, which plunged something like 54% in price,

has been hurt badly by a continuing series of problems. They just received

the bad news that they have to stop selling their anti-depressant drug,

Dutonin, in Europe. In 2002, Bristol's stock was severely damaged by the

havoc surrounding Erbitux, the colorectal drug manufactured by ImClone

Systems (IMCL), which Bristol purchased a 20% stake in.

Schering-Plough was hit very hard in 2002 because its main drug,

Claritin, an allergy treatment, went off-patent in December, thereby leading

to a potentially rapid decline in prescription sales.

Generally speaking, most of the big drug stocks missed their earnings

targets in 2002. Even companies that had better longer-term fundamentals

[like Pfizer and Johnson & Johnson (JNJ), which did not cut their earnings

guidances all year] traded down in sympathy with the group.

S&P: How did that affect your performance overall?

YELLEN: Our fund was actually not that badly hurt by the weakness

among the big drug stocks because we did not bulk up on them until the

middle of the year, after most of the damage had already been done.

What hurt us the most was our overweighting in hospital stocks, which

plunged in the fourth quarter. Tenet Healthcare (THC) collapsed in that last

quarter due to the controversy surrounding Medicare payments, and their

problems brought down the whole hospital sector.

On the biotech side, valuations were still quite high going into 2002.

This is a sector that will not perform well in a downward market. There was

a lot of negative news regarding biotech products. Given how volatile and

speculative biotech still is, it's not surprising they did so poorly in

2002.

The only bright spot in 2002 might have been with some medical technology

stocks, including the orthopedic and cardiac areas, which did reasonably

well, notably Boston Scientific (BSX) and Medtronic Inc. (MDT).

S&P: What are your top ten holdings?

YELLEN: As of December 31, our top ten stocks consisted of

Pharmacia Corp. (PHA), 7.1%; Pfizer Inc. (PFE), 6.0%; Community Health

Systems Inc. (CYH), 5.3%; Aventis (AVE), 5.2%; HCA Inc. (HCA), 5.1%; St.

Jude Medical Inc., 5.0%; Merck & Co. (MRK), 4.9%; Bristol-Myers Squibb (BMY),

4.8%; Amgen (AMGN), 4.7%; and Tenet Healthcare Corp. (THC), 4.6%. These ten

represented 52.7% of the portfolio's total assets as of the end of December.

We have 109 holdings overall.

S&P: What are your top sectors within health care?

YELLEN: Our largest sub-sectors as of December 31 were

pharmaceuticals, 49.5%; health care facilities, 19.5%; biotechnology, 8.2%;

health care equipment, 7.9%; diversified chemicals, 7.3%; managed health

care, 1.5%; and health care supplies, 1.5%.

S&P: What is your geographic allocation?

YELLEN: As the end of the year 71.2% of our assets were invested

in U.S. stocks. We also had 7.4% in France, 6.4% in Japan, and 4.3% in

Netherlands.

S&P: You mentioned the problems at Bristol-Myers, yet it is one of

your largest holdings.

YELLEN: We bought most of our position in Bristol-Myers in the

middle of last year, after the stock suffered the worst of the damage.

There's no getting around that Bristol is currently a screwed-up company

with problems on all fronts. We are certainly not bullish on Bristol, but

given its low valuation, the stock's 4.5% yield is very attractive.

Moreover, many investors see it as an obvious acquisition target, something

I don't think will necessarily happen.

S&P: Tell me about Pfizer, the world's largest drug company.

YELLEN: Pfizer has very strong fundamentals. The stock price

weakened in 2002, in tandem with the pharmaceutical sector as a whole. We

also own Pharmacia, which Pfizer will soon be acquiring. Therefore, it is by

far our largest holding.

Pfizer faces very little exposure to patent expiration issues over the

next five years. They have a very good and stable product pipeline,

including their blockbuster Lipitor. In addition, they are far outspending

their competitors in terms of marketing and R&D. The Pharmacia acquisition

will give them some scope for cost cutting.

We think Pfizer can deliver 17%-18% annual earnings growth for the

foreseeable future. Pfizer currently trades at a P/E multiple that is at a

discount to the overall market and to the drug sector. This just doesn't

make any sense. There's very little risk here with this stock.

S&P: Many patents are expiring on blockbuster drugs, opening up

competition from the low-cost generic drug-makers. Are you concerned about

this?

YELLEN: Patent expiration is definitely a serious factor that the

large-cap drug companies are having to face. However, in absolute terms, the

dollar sales amount of products lost to patent expiry peaked in 2002,

something on the order of $6 or $7 billion. If you look over the next couple

of years, these sales figures will decline pretty meaningfully, to something

like $2 or $3 billion by 2005. So, at the margins, the situation gets better

for the large-cap drug companies the next two or three years.

By 2006, more drug patents will expire, but given that we've seen new

products launched the past few years and expect a new roll-out of drugs over

the next few years, the dollar sales volume for the industry as a whole

should be increasing. In terms of earnings disappointments, I think we have

seen the worst of it in 2002. Given aging demographics in the developed

world and low stock price valuations, we still believe the large-cap drug

sector will provide relative outperformance.

S&P: You mentioned Tenet Healthcare (THC), which is facing a host

of legal battles. Why is it still in your fund?

YELLEN: Tenet Healthcare (THC) is under investigation for Medicare

billing and is facing a myriad of lawsuits. However, we think the company

can overcome these problems, and we have actually added to our position in

the stock. Given its valuation [P/E of about 7.6], I think all the potential

risks have already been discounted in the stock's price.

In addition, the company has taken many steps to rectify its legal

problems, and they've been quite candid with the investment community about

their strategy. I think the potential liabilities against Tenet will be

manageable. As the smoke clears, I think the stock will recover, and I trust

the management team will ably address all these issues. As such, we think

Tenet is a good long-term value.

If you compare the situation surrounding Tenet with what Columbia HCA

went through five or six years ago, it's not nearly as serious. And bear in

mind that back then, under a cloud of Federal probes, Columbia HCA's stock

bottomed out at a level that was higher than where Tenet trades today.

S&P: How do you view the HMOs?

YELLEN: We think United Healthcare (UNH) is the best run,

best-managed HMO with the best earnings visibility, the strongest

fundamentals, and least risk going forward. The HMO sector sold off in the

fourth quarter of last year, but it was one of the top-performing health

care groups in 2002.

However, we have some concerns with the fundamentals of HMOs as a whole.

We think they might be in a late-stage cycle of growth, and they will be

hard pressed to receive 15% to 20% premium rate increases from their

corporate clients, thus leading to declining margins.

The jury is still out on HMOs. Although we felt their fundamentals were

peaking in 2002, they have held up pretty well and delivered impressive

earnings across the board.

S&P: Tell me about one of your major foreign holdings.

YELLEN: Our biggest European holding is Aventis S.A. (AVE), a

French-based multi-national drug company with three main products: Allegra/Telfast,

an allergy drug; Lovenox/Clexane, an anti-thrombosis agent; and Taxotere, a

chemotherapy agent. The European Union recently approved the use of Taxotere

as a first-line treatment for patients with advanced non-small cell lung

cancer. The FDA granted a similar approval in December. Like its U.S.

counterparts, however, Aventis is facing such problems as trying to develop

new products and new growth from existing product lines to offset the loss

of sales of drugs which are going off-patent.

The company's stock is down about 40% from its 52-week high. This is

primarily due to concerns about Allegra, which may be hurt by

non-prescription sales of Claritin, a similar drug manufactured by

Schering-Plough [Schering began selling Claritin over-the-counter in the

U.S. in December]. However, we think the risk posed by Claritin has been

over-discounted with respect to Aventis' stock price. Overall, this company

will likely be one of the fastest growing foreign multi-national drug firms.

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